GTEx Portal

This TypeScript-based MCP server provides access to GTEx (Genotype-Tissue Expression) genomics data through 25 specialized tools organized into expression analysis, association analysis, and reference/dataset categories. Built with comprehensive TypeScript type definitions and a robust API client that handles GTEx Portal API v2 communication, it offers tools for gene expression profiling across tissues, eQTL/sQTL genetic association analysis, variant lookups, and dataset metadata retrieval with features like error handling, pagination, and parameter validation. The implementation targets genomics researchers, bioinformaticians, and AI assistants working with human gene expression data who need programmatic access to one of the largest publicly available genomics datasets for tissue-specific expression analysis, genetic variant associations, and comparative genomics studies.